Looking for the best lactose-free formulas for your baby? We’ve researched and compared top brands to help you find the perfect, gentle option for your little one’s needs.
Choosing the right lactose-free formula for your baby can feel overwhelming. Many babies have sensitive tummies or milk allergies, making it crucial to find a formula that’s gentle and nourishing. We’ve done the research to help you make the best choice.
Lactose-free formulas ease fussiness, gas, and colic, so your baby feels comfortable. They also provide essential nutrients for healthy growth. With so many options, it’s easy to find one that fits your baby’s needs.
We’ve tested and compared top brands like Enfamil, Similac, and Mama Bear. Our guide highlights hypoallergenic, plant-based, and soy-based options, ensuring you find the perfect match. Let’s make feeding time stress-free for you and your little one!
List of Top 10 Lactose Free Formulas
| Image | Title | Best For | Price |
|---|---|---|---|
![]() |
Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow’s Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 19.8 Oz Can |
This formula is perfect for babies with cow’s milk allergy who need fast relief from colic. It is also great for parents who want immune and brain support for their little one. |
|
![]() |
Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow’s Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 27.8 Oz Can |
This formula is perfect for babies with cow’s milk allergy or colic. It helps ease discomfort and supports brain and immune health. |
|
![]() |
Enfamil Prosobee Plant based Baby Formula, for Sensitive Tummies, Soy-based Plant Sourced Protein, Vitamins for Immune Support, Lactose-free, Milk free, Gluten free, 20.9 Oz Can |
Enfamil Prosobee is perfect for babies with sensitive tummies or milk sensitivity. It’s also great for families following vegetarian or Kosher diets. |
|
![]() |
Good Start | Dr. Brown’s Soy-ease Pro Baby Formula Powder, for Sensitive Tummies, Dairy Free and Lactose Free for Fussiness and Gas, Non-GMO, 20 Oz |
Good Start | Dr. Brown’s Soy-ease Pro Baby Formula Powder is perfect for parents with babies who have sensitive tummies. It’s ideal for fussiness and gas caused by milk or lactose sensitivity. |
|
![]() |
Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow’s Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 27.8 Oz, 4 Count |
This formula is perfect for babies with cow’s milk allergy or colic. It helps ease discomfort and supports brain and immune health. |
|
![]() |
Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow’s Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 12.6 Oz Can |
This formula is perfect for babies with cow’s milk allergy. It is great for colic relief and helps build the brain while supporting the immune system. |
|
![]() |
Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow’s Milk Allergy Starts in 24 Hours, Brain Building DHA, Concentrated Liquid, 8 Fl Oz, 24 Bottles |
This formula is perfect for babies with cow’s milk allergy or colic. It’s also great for parents who want fast relief and brain-boosting nutrition. |
|
![]() |
Amazon Brand – Mama Bear Soy Based Powder Infant Formula with Iron, for Fussiness & Gas, Lactose-Free, 22 ounce (Pack of 1) |
This lactose-free formula is perfect for babies who are sensitive to lactose. It helps reduce fussiness and gas, making it ideal for parents seeking a comfortable solution for their little ones. |
|
![]() |
Enfamil Prosobee Plant based Baby Formula, for Sensitive Tummies, Soy-based Plant Sourced Protein, Vitamins for Immune Support, Lactose-free, Milk free, Gluten free, 32 Fl Oz Bottle (4 count) |
This plant-based baby formula is perfect for babies with sensitive tummies. It’s lactose-free, milk-free, and gluten-free, making it a great choice for little ones with dietary needs. |
|
![]() |
Similac 360 Total Care Sensitive Infant Formula for Fussiness & Gas Due to Lactose Sensitivity, Has 5 HMO Prebiotics, Baby Formula, Ready to Feed, 2-fl-oz Bottle, Pack of 12 |
This formula is perfect for babies with sensitive tummies. It helps with fussiness and gas and is easy to digest. |
Detailed Reviews
Discover the top 10 lactose-free formulas carefully selected for your baby’s comfort and health. Each formula is expert-reviewed and backed by real parent feedback, ensuring you find the perfect match. Whether you’re dealing with allergies or sensitive tummies, this guide makes choosing easy and stress-free.
1. Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow’s Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 19.8 Oz Can

Enfamil Nutramigen is a hypoallergenic baby formula designed for infants with cow’s milk allergy. It’s lactose-free and helps ease colic quickly. This formula is amino acid-based for easy digestion.
It includes LGG, a probiotic that supports digestive health and allergy management. The formula also has brain-building nutrients like DHA, ARA, and Choline.
Nutramigen provides immune support to help babies tolerate traditional milk protein again. It’s a gentle, effective solution for happier, healthier babies.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This formula is perfect for babies with cow’s milk allergy who need fast relief from colic. It is also great for parents who want immune and brain support for their little one.
Ready to Purchase?
2. Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow’s Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 27.8 Oz Can

Enfamil Nutramigen is a hypoallergenic baby formula designed for infants with cow’s milk allergy. It provides fast colic relief, often starting within 24 hours.
This formula is lactose-free and amino acid-based. It includes DHA for brain support and probiotic LGG for immune health.
Nutramigen helps babies return to traditional formula without allergic reactions. It’s a gentle, effective solution for happier babies and moms.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This formula is perfect for babies with cow’s milk allergy or colic. It helps ease discomfort and supports brain and immune health.
Ready to Purchase?
3. Enfamil Prosobee Plant based Baby Formula, for Sensitive Tummies, Soy-based Plant Sourced Protein, Vitamins for Immune Support, Lactose-free, Milk free, Gluten free, 20.9 Oz Can

Enfamil Prosobee is a dairy-free baby formula made from soy-based protein. It’s perfect for babies with sensitive tummies or milk allergies.
This formula is lactose-free, milk-free, and gluten-free, helping ease fussiness, gas, and colic. It also supports brain development with DHA and boosts the immune system with added vitamins.
Kosher and vegetarian-friendly, it’s great for special diets. Pediatrician-recommended and SNAP-eligible, it’s a trusted choice for families.
| Pros | Cons |
|---|---|
|
|
Perfect For:
Enfamil Prosobee is perfect for babies with sensitive tummies or milk sensitivity. It’s also great for families following vegetarian or Kosher diets.
Ready to Purchase?
4. Good Start | Dr. Brown’s Soy-ease Pro Baby Formula Powder, for Sensitive Tummies, Dairy Free and Lactose Free for Fussiness and Gas, Non-GMO, 20 Oz

Good Start | Dr. Brown’s Soy-ease Pro Baby Formula is a dairy-free and lactose-free option for babies. It’s made to help with fussiness and gas caused by sensitive tummies.
This formula uses 100% plant-based proteins, which are gentle on tiny tummies. It’s milk and lactose free, perfect for babies with sensitivities. It also includes DHA to support brain and eye growth.
Soy-ease Pro gives complete nutrition for babies aged 0-12 months. It’s non-GMO and helps with growth and development. This formula is a trusted choice for sensitive babies.
| Pros | Cons |
|---|---|
|
|
Perfect For:
Good Start | Dr. Brown’s Soy-ease Pro Baby Formula Powder is perfect for parents with babies who have sensitive tummies. It’s ideal for fussiness and gas caused by milk or lactose sensitivity.
Ready to Purchase?
5. Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow’s Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 27.8 Oz, 4 Count

Enfamil Nutramigen is a hypoallergenic baby formula designed for infants with cow’s milk allergy. It provides fast colic relief, often starting within 24 hours.
This formula is lactose-free and amino acid-based. It includes DHA for brain support and probiotic LGG for immune health.
With Nutramigen, babies get essential nutrients like those in breast milk. It helps them grow strong and stay healthy.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This formula is perfect for babies with cow’s milk allergy or colic. It helps ease discomfort and supports brain and immune health.
Ready to Purchase?
6. Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow’s Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 12.6 Oz Can

Enfamil Nutramigen is a special formula for babies with cow’s milk allergy. It’s lactose-free and has iron for healthy growth. This formula starts to relieve colic in as early as the first feeding.
It’s clinically proven to reduce allergy challenges in the future. With 90% of infants improving within 48 hours, it’s a fast and effective solution. The formula also supports immune health with probiotic LGG.
Brain-building DHA is included for healthy development. This formula helps babies return to consuming milk protein without an allergic response. It’s a trusted choice for parents seeking fast relief and long-term benefits.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This formula is perfect for babies with cow’s milk allergy. It is great for colic relief and helps build the brain while supporting the immune system.
Ready to Purchase?
7. Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow’s Milk Allergy Starts in 24 Hours, Brain Building DHA, Concentrated Liquid, 8 Fl Oz, 24 Bottles

Enfamil Nutramigen is a hypoallergenic baby formula designed to ease colic caused by cow’s milk allergy. It’s lactose-free and ready-to-feed, making it convenient for busy parents. This formula also supports brain development with DHA, ARA, and choline.
It’s trusted by pediatricians and SNAP eligible, so it’s accessible for families. Plus, you can subscribe and save for extra convenience and savings.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This formula is perfect for babies with cow’s milk allergy or colic. It’s also great for parents who want fast relief and brain-boosting nutrition.
Ready to Purchase?
8. Amazon Brand – Mama Bear Soy Based Powder Infant Formula with Iron, for Fussiness & Gas, Lactose-Free, 22 ounce (Pack of 1)

Mama Bear Soy Baby Formula is lactose-free, perfect for babies sensitive to lactose. It’s a gentle choice for tiny tummies. Compare it to Similac Soy Isomil & Enfamil ProSobee.
This formula reduces fussiness and gas, helping babies feel more comfortable. It’s complete nutrition for babies from birth to 12 months. Plus, it’s gluten-free and 100% soy protein.
The formula includes vitamins, minerals, and DHA for growth. It also has prebiotics to support a healthy digestive system. Mama Bear gives your baby everything they need.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This lactose-free formula is perfect for babies who are sensitive to lactose. It helps reduce fussiness and gas, making it ideal for parents seeking a comfortable solution for their little ones.
Ready to Purchase?
9. Enfamil Prosobee Plant based Baby Formula, for Sensitive Tummies, Soy-based Plant Sourced Protein, Vitamins for Immune Support, Lactose-free, Milk free, Gluten free, 32 Fl Oz Bottle (4 count)

Enfamil Prosobee is a plant-based baby formula made with soy protein. It’s lactose-free, milk-free, and gluten-free, perfect for sensitive tummies. This formula provides complete nutrition for babies up to 12 months.
It supports brain development with DHA, just like Enfamil’s routine formula. Pediatricians recommend Enfamil as the #1 infant formula.
The ready-to-use bottles are great for on-the-go moms or late-night feedings. You can also buy it with SNAP benefits or save more with Subscribe & Save.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This plant-based baby formula is perfect for babies with sensitive tummies. It’s lactose-free, milk-free, and gluten-free, making it a great choice for little ones with dietary needs.
Ready to Purchase?
10. Similac 360 Total Care Sensitive Infant Formula for Fussiness & Gas Due to Lactose Sensitivity, Has 5 HMO Prebiotics, Baby Formula, Ready to Feed, 2-fl-oz Bottle, Pack of 12

Similac 360 Total Care Sensitive Infant Formula is made for babies with lactose sensitivity. It helps reduce fussiness and gas. Each bottle is ready to feed and is convenient for parents.
This formula contains 5 HMO prebiotics to support your baby’s immune system. It is also gluten-free and hormone-free.
The product comes in 2-fl-oz bottles and is available in a pack of 12. It is suitable for babies with special dietary needs.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This formula is perfect for babies with sensitive tummies. It helps with fussiness and gas and is easy to digest.
Ready to Purchase?
Buying Guide
Choosing the right lactose-free formula is easy with our guide. We’ve tested top brands to help you find the best fit. Let’s make feeding time stress-free for you and your baby!
Factors to Consider When Buying Lactose-Free Formulas
- Baby’s Needs: Check if your baby has milk allergies, sensitive tummies, or lactose intolerance. Choose a formula that matches their specific needs.
- Formula Type: Decide between hypoallergenic, soy-based, or plant-based options. Each type offers unique benefits for different babies.
- Nutrients: Look for DHA, ARA, and vitamins to support brain development and immune health.
- Ease of Digestion: Pick formulas with probiotics or prebiotics to help with fussiness, gas, and colic.
- Convenience: Consider ready-to-feed bottles or powder formulas based on your lifestyle and ease of use.
- Dietary Restrictions: Ensure the formula is gluten-free, kosher, or vegetarian-friendly if needed.
- Brand Reputation: Choose trusted brands like Enfamil, Similac, or Mama Bear for quality and safety.
- Cost and Accessibility: Check if the formula is SNAP-eligible or offers subscription savings for budget-friendly options.